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1

9-Methyl-β-carboline-induced cognitive enhancement is associated with elevated hippocampal dopamine levels and dendritic and synaptic proliferation

Michael Gruss, Dorothea Appenroth, Armin Flubacher, Christoph Enzensperger, Jörg Bock, Christian Fleck, Gabriele Gille, Katharina Braun

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

2

Beta and gamma carboline derivatives as potential anti-Alzheimer agents: A comparison

Otto, Robert, Penzis, Robert, Gaube, Friedemann, Winckler, Thomas, Appenroth, Dorothea, Fleck, Christian, Tränkle, Christian, Lehmann, Jochen, Enzensperger, Christoph

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 565 KB

english, 2014

3

Ontogenetic Aspects of Thallium-induced Nephrotoxicity in Rats

Dorothea Appenroth, Silke Tiller, Stepan Gambaryan, Klaus Winnefeld, Christian Fleck, Helmut Bräunlich

Journal:

Journal of Applied Toxicology

Year:

1996

Language:

english

File:

PDF, 803 KB

english, 1996

4

Protective Effects of Methimazole against Cisplatin-induced Nephrotoxicity in Rats

Helmut Bräunlich, Dorothea Appenroth, Christian Fleck

Journal:

Journal of Applied Toxicology

Year:

1997

Language:

english

File:

PDF, 159 KB

english, 1997

5

Is thallium-induced nephrotoxicity in rats connected with riboflavin and/or GSH?—reconsideration of hypotheses on the mechanism of thallium toxicity

Dorothea Appenroth, Klaus Winnefeld

Journal:

Journal of Applied Toxicology

Year:

1999

Language:

english

File:

PDF, 84 KB

english, 1999

6

ChemInform Abstract: Tacrine-NO donor (I) and Tacrine-Ferulic Acid Hybrid (II) Molecules as New anti-Alzheimer Agents: Hepatotoxicity and Influence on the Cytochrome P450 System in Comparison to Tacrine.

Amelie Lupp, Dorothea Appenroth, Lei Fang, Michael Decker, Jochen Lehmann, Christian Fleck

Journal:

Year:

2010

File:

PDF, 74 KB

2010

7

Triiodothyronine (T3) increases cisplatin nephrotoxicity in young and adult rats

Dorothea Appenroth, Stephan Gambaryan, Vera Bakhteeva, Klaus Winnefeld, Heinz Schröter, Steffen Gerhardt, Helmut Bräunlich

Journal:

Journal of Applied Toxicology

Year:

1990

Language:

english

File:

PDF, 368 KB

english, 1990

8

Beneficial effect of acetylcysteine on cisplatin nephrotoxicity in rats

Dorothea Appenroth, Klaus Winnefeld, Heinz Schröter, Michael Rost

Journal:

Journal of Applied Toxicology

Year:

1993

Language:

english

File:

PDF, 369 KB

english, 1993

9

Influence of high-dose methotrexate therapy (HD-MTX) on glomerular and tubular kidney function

Lutz Hempel, Joachim Misselwitz, Christian Fleck, Karim Kentouche, Christiane Leder, Dorothea Appenroth, Michael Rost, Felix Zintl

Journal:

Pediatric Blood & Cancer

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

10

Age differences in cisplatinum nephrotoxicity

Dorothea Appenroth, Helmut Bräunlich

Journal:

Year:

1984

Language:

english

File:

PDF, 550 KB

english, 1984

11

Functional and morphological aspects of thallium-induced nephrotoxicity in rats

Dorothea Appenroth, Stepan Gambaryan, Klaus Winnefeld, Matthias Leiterer, christian Fleck, Helmut Bräunlich

Journal:

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

12

The ambiguous effect of ascorbic acid on chromate induced proteinuria in rats

Dorothea Appenroth, Klaus Winnefeld, Heinz Schröter, Michael Rost

Journal:

Archives of Toxicology

Year:

1994

Language:

english

File:

PDF, 462 KB

english, 1994

13

Contribution to the mechanism of chromate nephrotoxicity in developing rats: EPR investigations

Dorothea Appenroth, Michael Rost, Manfred Friedrich, Oliver Schulz

Journal:

Archives of Toxicology

Year:

1996

Language:

english

File:

PDF, 256 KB

english, 1996

14

Immunocytochemical characterization of the incubated rat renal cortical slices

Vladiana Crljen, Ivana Sabolić, Jelena Sušac, Dorothea Appenroth, Carol M. Herak-Kramberger, Marija Ljubojević, Naohiko Anzai, Roberto Antolović, Gerhard Burckhardt, Christian Fleck, Ivan Sabolić

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 1.06 MB

english, 2005

15

Suitability of 5/6 nephrectomy (5/6NX) for the induction of interstitial renal fibrosis in rats – Influence of sex, strain, and surgical procedure

Christian Fleck, Dorothea Appenroth, Patrick Jonas, Mark Koch, Günther Kundt, Horst Nizze, Günter Stein

Journal:

Experimental and Toxicologic Pathology

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

16

Vitamin E and C in the prevention of metal nephrotoxicity in developing rats

Dorothea Appenroth, Klaus Winnefeld

Journal:

Experimental and Toxicologic Pathology

Year:

1998

Language:

english

File:

PDF, 5.53 MB

english, 1998

17

Renal interstitial fibrosis (RIF): II. Ultrasound follow up study of single uranyl nitrate administration causing renal dysfunction in rats – comparison with histologic and functional renal parameters

Marlies Fleck, Dorothea Appenroth, Ansgar Malich, Günter Stein, Christian Fleck

Journal:

Experimental and Toxicologic Pathology

Year:

2002

Language:

english

File:

PDF, 2.77 MB

english, 2002

18

Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy

Dorothea Appenroth, Ralf Beutinger, Amelie Lupp, Christian Fleck

Journal:

Experimental and Toxicologic Pathology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

19

RT-PCR-based evidence for the in vivo stimulation of renal tubular p-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats

Andrew Bahn, Achim Hauss, Dorothea Appenroth, Diana Ebbinghaus, Yohannes Hagos, Peter Steinmetzer, Gerhard Burckhardt, Christian Fleck

Journal:

Experimental and Toxicologic Pathology

Year:

2003

Language:

english

File:

PDF, 90 KB

english, 2003

20

Determination of renal porphyrin handling in rats suffering from different kinds of chronic renal failure (CRF): Uranyl nitrate (UN) induced fibrosis or 5/6-nephrectomy (5/6NX)

Christian Fleck, Thorsten Scholle, Markus Schwertfeger, Dorothea Appenroth, Günter Stein

Journal:

Experimental and Toxicologic Pathology

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

21

Use of gene chip technology for the characterisation of the regulation of renal transport processes and of nephrotoxicity in rats

Christian Fleck, Laura Sutter, Dorothea Appenroth, Berit Koch, Tobias Meinhold, Melanie Pitack, Rodolfo Gasser

Journal:

Experimental and Toxicologic Pathology

Year:

2003

Language:

english

File:

PDF, 74 KB

english, 2003

22

Riboflavin can decrease the nephrotoxic effect of chromate in young and adult rats

Dorothea Appenroth, Oliver Schulz, Klaus Winnefeld

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 552 KB

english, 1996

23

LLU-α, an endogenous metabolite of γ-tocopherol, is more effective against metal nephrotoxicity in rats than γ-tocopherol

Dorothea Appenroth, Elke Karge, Grit Kießling, William J Wechter, Klaus Winnefeld, Christian Fleck

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 354 KB

english, 2001

24

NO-Donating Tacrine Hybrid Compounds Improve Scopolamine-Induced Cognition Impairment and Show Less Hepatotoxicity

Fang, Lei, Appenroth, Dorothea, Decker, Michael, Kiehntopf, Michael, Lupp, Amelie, Peng, Sixun, Fleck, Christian, Zhang, Yihua, Lehmann, Jochen

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.44 MB

english, 2008

25

Hybrid Molecules from Xanomeline and Tacrine: Enhanced Tacrine Actions on Cholinesterases and Muscarinic M 1 Receptors

Fang, Lei, Jumpertz, Sabine, Zhang, Yihua, Appenroth, Dorothea, Fleck, Christian, Mohr, Klaus, Tränkle, Christian, Decker, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

26

Synthesis and Biological Evaluation of NO-Donor-Tacrine Hybrids as Hepatoprotective Anti-Alzheimer Drug Candidates

Fang, Lei, Appenroth, Dorothea, Decker, Michael, Kiehntopf, Michael, Roegler, Carolin, Deufel, Thomas, Fleck, Christian, Peng, Sixun, Zhang, Yihua, Lehmann, Jochen

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

27

Ultrastructural and ultraimmunohistochemical changes upon partial nephrectomy and uranyl intoxication in the rat kidney

Oehring, Hartmut, Widder, Julia, Appenroth, Dorothea, Jirikowski, Gustav F., Fleck, Christian

Journal:

Experimental and Toxicologic Pathology

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

28

The activity of chromate reduction in renal tissue corresponds to chromate nephrotoxicity — developmental aspects

Kersten, Lothar, Appenroth, Dorothea

Journal:

Toxicology Letters

Year:

1990

Language:

english

File:

PDF, 175 KB

english, 1990

29

Role of Glutathione for Cisplatin Nephrotoxicity in Young and Adult Rats

Appenroth, Dorothea, Winnefeld, Klaus

Journal:

Year:

1993

Language:

english

File:

PDF, 413 KB

english, 1993

30

Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders

Otto, Robert, Penzis, Robert, Gaube, Friedemann, Adolph, Oliver, Föhr, Karl J., Warncke, Paul, Robaa, Dina, Appenroth, Dorothea, Fleck, Christian, Enzensperger, Christoph, Lehmann, Jochen, Winckler, T

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 434 KB

english, 2015

31

Tacrine-NO donor and tacrine-ferulic acid hybrid molecules as new anti-Alzheimer agents: hepatotoxicity and influence on the cytochrome P450 system in comparison to tacrine

Amelie, Lupp, Dorothea, Appenroth, Lei, Fang, Michael, Decker, Jochen, Lehmann, Christian, Fleck

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

32

Investigation into the in vivo effects of five novel tacrine/ferulic acid and β-carboline derivatives on scopolamine-induced cognitive impairment in rats using radial maze paradigm

Fleck, Christian, Appenroth, Dorothea, Fang, Lei, Schott, Yvonne, Lehmann, Jochen, Decker, Michael

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 425 KB

english, 2011

33

Influence of age on cognition and scopolamine induced memory impairment in rats measured in the radial maze paradigm

Appenroth, Dorothea, Fleck, Christian

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

34

Fibronectin Splice Variants – Prognostic Markers for the Stage of Renal Interstitial Fibrosis in the Rat

Eismann, Ulrike, Sommer, Manfred, Kosmehl, Hartwig, Appenroth, Dorothea, Fleck, Christian, Stein, Günter

Journal:

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

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